Nicholas H Oberlies Selected Research

verticillins

4/2021	Semisynthetic Derivatives of the Verticillin Class of Natural Products through Acylation of the C11 Hydroxy Group.
1/2020	Verticillin A Causes Apoptosis and Reduces Tumor Burden in High-Grade Serous Ovarian Cancer by Inducing DNA Damage.
1/2018	Contrasting roles of H3K4me3 and H3K9me3 in regulation of apoptosis and gemcitabine resistance in human pancreatic cancer cells.
8/2015	H3K9 Trimethylation Silences Fas Expression To Confer Colon Carcinoma Immune Escape and 5-Fluorouracil Chemoresistance.

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Nicholas H Oberlies Research Topics

Disease

31	Neoplasms (Cancer) 01/2022 - 02/2004
13	Infections 01/2019 - 05/2009
12	Prostatic Neoplasms (Prostate Cancer) 01/2020 - 05/2005
8	Carcinoma (Carcinomatosis) 10/2021 - 05/2005
4	Liver Diseases (Liver Disease) 04/2014 - 02/2010
4	Hepatocellular Carcinoma (Hepatoma) 11/2013 - 03/2010
3	Mesothelioma 01/2022 - 01/2017
3	Lung Neoplasms (Lung Cancer) 10/2021 - 02/2004
3	Ovarian Neoplasms (Ovarian Cancer) 01/2020 - 02/2004
3	Pancreatic Neoplasms (Pancreatic Cancer) 01/2018 - 01/2017
3	Breast Neoplasms (Breast Cancer) 01/2017 - 07/2012
3	Inflammation (Inflammations) 01/2016 - 01/2011
2	Non-alcoholic Fatty Liver Disease 06/2021 - 04/2014
2	Type 2 Diabetes Mellitus (MODY) 06/2021 - 04/2014
2	Colonic Neoplasms (Colon Cancer) 01/2019 - 07/2012
2	Adenocarcinoma 01/2018 - 12/2006
2	Body Weight (Weight, Body) 01/2012 - 12/2008
2	Glioblastoma (Glioblastoma Multiforme) 04/2007 - 12/2006
1	Pain (Aches) 03/2022
1	Disease Progression 01/2022
1	Margins of Excision 10/2021
1	Lewis Lung Carcinoma 10/2021
1	Actinic Keratosis 11/2020
1	Mycoses (Diseases, Fungus) 11/2020
1	Aspergillosis 10/2020
1	Bacterial Infections (Bacterial Infection) 01/2019
1	Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder) 01/2019
1	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2019
1	Dehydration (Water Stress) 10/2018
1	Peritoneal Neoplasms 12/2017
1	Tinea (Ringworm) 10/2017
1	Lymphatic Metastasis 01/2017

Drug/Important Bio-Agent (IBA)

17	SilymarinIBA 01/2019 - 05/2005
11	Pharmaceutical PreparationsIBA 11/2020 - 12/2006
8	Silybin (Lagosa)IBA 11/2013 - 05/2005
6	Biological ProductsIBA 06/2021 - 05/2005
5	FlavonolignansIBA 02/2013 - 05/2005
5	isosilybin AIBA 10/2010 - 05/2005
4	verticillinsIBA 04/2021 - 08/2015
3	Anti-Bacterial Agents (Antibiotics)IBA 01/2019 - 03/2015
3	CytokinesIBA 01/2016 - 02/2010
3	milk-thistle extractIBA 01/2012 - 11/2007
2	EnzymesIBA 01/2022 - 01/2022
2	Glucosephosphate Dehydrogenase (Glucose 6 Phosphate Dehydrogenase)IBA 01/2022 - 01/2022
2	Immune Checkpoint InhibitorsIBA 01/2022 - 01/2019
2	NF-kappa B (NF-kB)IBA 01/2022 - 03/2010
2	Antineoplastic Agents (Antineoplastics)IBA 10/2021 - 07/2012
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2019 - 07/2012
2	PeptaibolsIBA 10/2018 - 08/2012
2	histone H3 trimethyl Lys4IBA 01/2018 - 01/2017
2	CaspasesIBA 01/2018 - 07/2012
2	Paclitaxel (Taxol)FDA LinkGeneric 01/2017 - 02/2004
2	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 07/2013 - 02/2013
2	Proteins (Proteins, Gene)FDA Link 06/2010 - 02/2010
2	Antiviral Agents (Antivirals)IBA 06/2010 - 02/2010
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 03/2010 - 02/2010
1	Opioid Analgesics (Opioids)IBA 03/2022
1	MycotoxinsIBA 01/2022
1	monorden (radicicol)IBA 01/2022
1	Granzymes (Granzyme)IBA 01/2022
1	hypothemycinIBA 01/2022
1	L 783277IBA 01/2022
1	7-oxozeanolIBA 01/2022
1	monocillin IIIBA 01/2022
1	Lactate Dehydrogenase 5IBA 01/2022
1	Acetyl Coenzyme A (Acetyl-CoA)IBA 01/2022
1	ZearalenoneIBA 01/2022
1	Phosphotransferases (Kinase)IBA 01/2022
1	Coenzyme A (CoA)IBA 01/2022
1	eupenifeldinIBA 10/2021
1	PolymersIBA 10/2021
1	AlkaloidsIBA 04/2021
1	Virulence Factors (Pathogenicity Factors)IBA 11/2020
1	3-ingenyl angelateIBA 11/2020
1	fumagillinIBA 10/2020
1	pseurotinIBA 10/2020
1	Qa-SNARE Proteins (Syntaxin)IBA 01/2020
1	enzalutamideIBA 01/2020
1	Cytotoxins (Cytolysins)IBA 01/2019
1	apicidinIBA 01/2019
1	Histone MethyltransferasesIBA 01/2019
1	Oxygen (Dioxygen)IBA 01/2019
1	Glutamine (L-Glutamine)FDA Link 10/2018
1	Alanine (L-Alanine)FDA Link 10/2018
1	NitrilesIBA 10/2018
1	PalladiumIBA 10/2018
1	AmidesIBA 10/2018
1	Bcl-2-Like Protein 11IBA 01/2018
1	Cytochromes c (Cytochrome c)IBA 01/2018
1	Gemcitabine FDA Link 01/2018
1	Griseofulvin (Grifulvin V)FDA LinkGeneric 10/2017
1	Fluorescent Dyes (Fluorescent Probes)IBA 01/2017
1	FluorineIBA 01/2017

Therapy/Procedure

7	Therapeutics 01/2022 - 04/2007
4	Immunotherapy 01/2022 - 01/2017
4	Drug Therapy (Chemotherapy) 10/2021 - 06/2007
4	Chemoprevention 09/2015 - 06/2007
1	Castration 01/2020
1	Radiotherapy 01/2018
1	Catheters 12/2017